Panicale, as it is the case for most of the villages of the region, still maintains a medieval aspect due typically to the remains of the old town walls and the fortified doors.
Although the churches of the Madonna of the Slabs and the one of S.Augustin are remarkable buildings, the main attraction of the village has to be found in the magnificent views one can benefit of the Trasimeno Lake and the valley of the Nestore torrent. However, artistic works are more interesting, and good reasons to visit the church of S. Sebastiano where there are two Perugino frescoes: "Martyrdom of St. Sebastiano" and "Incoronazione di Maria" as well as the beautiful facade of the Collegiata, which is located in St. Michele square.